Silkron is a familiar topical drug used in many dermatological lesions such as dermatitis, tinea versicolor. Due to the packaging design characterized by the line dividing 7 color cells, Silkron is often referred to by users by the easy-to-remember name "7-color medicine". Silkron 7-color has many uses, but the effect is only optimal when users know the product characteristics and how to use it most accurately.
II. Ingredients - uses
- Silkron 7-color medicine contains the main active ingredients: betamethasone dipropionate, clotrimazole, gentamicin sulfate
1. Betamethasone dipropionate
Betamethasone is a synthetic corticosteroid with very strong glucocorticoid effects. Active ingredients have anti-inflammatory, anti-rheumatic and anti-allergic effects, high doses have immunosuppressive effects.
Clotrimazole binds to phospholipids in the fungal cell membrane, alters membrane permeability, causes loss of essential intracellular substances leading to fungal cell death. This is a broad-spectrum antifungal agent used to treat skin diseases caused by infection with various pathogenic fungi, effective on Trichomonas, Staphylococcus and Bacteroides.
3. Gentamicin sulphate
It is a natural antibiotic belonging to the aminoside group that has a bactericidal effect through inhibiting the protein biosynthesis of bacteria. Gentamicin is active against gram-negative aerobic bacteria, staphylococci, including penicillinase-producing and methicillin-resistant strains.
Thus, 7-color silkron drug works:
- Anti-inflammatory, anti-allergic, immunosuppressive.
- Kills fungal and bacterial cells.
III. 4 most common indications of 7 color pills
Containing corticosteroids and strong antibiotics, silkron 7 color medicine is indicated for use in the following cases:
1. Used for skin infections: impetigo, diaper rash, folliculitis
- With skin infections, the main cause of the disease is bacteria. Therefore, gentamycin in 7-color medicine effectively destroys pathogens, good treatment in cases: impetigo, diaper rash, folliculitis .
2. Used for fungal skin diseases
- The main cause of fungal skin diseases is an overgrowth of the fungus. Some skin infections caused by fungi are: ringworm, ringworm, onychomycosis, etc. Clotrimazol is present in the 7-color medicine to help kill those pathogenic fungi. At the same time, the betamethasone ingredient helps to effectively reduce inflammation and itching. 7 color medicine for ringworm
3. Inflammation caused by eczema or atopic dermatitis, psoriasis, urticaria
- Betamethasone helps relieve itching, reduce irritation, reduce redness caused by eczema, atopic dermatitis, psoriasis, urticaria. The immunosuppressive mechanism of corticosteroids provides a rapid effect on eczematous skin lesions. In addition, the antibiotic ingredient gentamicin helps prevent the risk of eczema and also eliminates some of the causes of skin irritation. 7 color medicine to treat itching caused by urticaria
4. 7 color pills for acne
- In addition to the above indications, 7-color medicine also works to kill the bacteria that cause acne, reduce swelling, heat, redness, pain, fly away inflammatory acne, cystic acne, ... causing discomfort for everyone. However, because it contains corticosteroids, Silkron should only be used on the face with caution. Users should consult their doctor carefully before applying acne treatment with Silkron. 7 color pills to treat acne
IV. Usage and dosage
- Step 1: Clean the affected skin with physiological saline 0.9% NaCl. Use a clean cloth.
- Step 2: Wash your hands with soap before applying the medicine.
- Step 3: Take an appropriate amount of the medicine and apply it evenly on the cleansed skin. Gently massage the medicine into the skin.
- Step 4: Wash your hands again, cover carefully, avoid the medicine getting into other healthy skin.
- Depending on the response to treatment and the extent of the injury, the dose may vary from person to person. Do not use the drug for more than 2 weeks because the absorption of the drug may increase, causing unwanted effects on the whole body. The amount of topical medication is also recommended not to use more than 45g / week. Users need to consult a doctor about the most appropriate dosage for each subject.
V. Undesirable effects
- Because the drug contains ingredients with strong medicinal properties, during use may occur undesirable effects as follows:
- Local side effects: burning sensation, slight burning, itching, irritation, folliculitis, hair growth, skin atrophy, skin rash,....
- When used in high doses and long term, the drug can be absorbed into the bloodstream and cause systemic side effects:
- Metabolic: loss of potassium, retention of water and sodium causing edema.
- Endocrine: irregular menstruation, cushing's syndrome, inhibition of fetal and infant growth, impaired glucose tolerance.
- Musculoskeletal: muscle weakness, loss of muscle mass, osteoporosis.
VI. Contraindications – caution
- Do not use the drug for the following cases:
- Hypersensitivity to the ingredients in the drug 7 colors.
- Eczema of the outer ear with a perforated eardrum
- Dermatitis develops with sores, signs of superinfection.
- Do not use 7-color medicine for children under 1 year old.
- Do not use for open wounds, avoid contact with eyes, mucous membranes, ears.
- Do not use 7-color medicine for infected wounds
- Pay attention to patient monitoring during prolonged treatment, especially children.
- Prolonged or repeated use may cause secondary bacterial infections.
- Must be treated for a long time, do not arbitrarily stop the drug even though the symptoms are relieved.
- If irritation or sensitization occurs, the drug should be discontinued and appropriate treatment instituted.
- Use of gentamicin may cause overgrowth of non-susceptible microorganisms including fungi. If superinfection occurs, the drug should be discontinued and appropriate other measures taken.
VII. Drug interactions
If used in high doses and for a long time, each active ingredient in 7-color pills will have the risk of interacting with other drugs, the risk of increasing the toxicity of each other.
1. Betamethasone dipropionate
- Concomitant use with high doses of paracetamol: increased risk of hepatotoxicity.
- NSAIDs such as ibuprofen, diclofenac, etc. increase the risk of peptic ulcers.
- Tricyclic antidepressants: increase corticosteroid-induced psychosis.
- Antidiabetic drugs: The dose of hypoglycemic agents should be adjusted after cessation of corticosteroid therapy.
- Glycosides digitalis: increased potential for arrhythmias or digitalis toxicity with hypokalemia.
Serum concentrations of tacrolimus in liver transplant patients are increased when co-administered with clotrimazol. Therefore, the dose of tacrolimus should be reduced as needed.
3. Gentamicin sulphate
- Concomitant use with other aminosides, vancomycin and cephalosporin antibiotics: nephrotoxicity.
- Ethacrynic acid, furosemide: ototoxic.
VIII. Notes when taking medicine
1. General Note
- Follow your doctor's instructions on dosage, duration, and usage.
- Avoid contact with other healthy skin, mucous membranes, ears, eyes.
- Avoid sources of infection or reinfection. Avoid wearing tight clothing on the treated wound.
- Avoid bandaging the skin where the medicine is applied, to create a certain ventilation.
- Wash your hands thoroughly before and after applying 7 colors. Medical gloves can be equipped when applying the medicine. Wash your hands thoroughly before and after applying 7 color medicine
- Do not wash the treated area after applying the cream. Avoid using other products on that area without your doctor's prescription.
- Consult a doctor when using this medicine on open wounds, dry, cracked, easily irritated or sunburned skin.
2. Note for special objects
The benefits and risks of the drug to the mother and fetus should be weighed.
The benefit to the mother must be weighed against the potential harm to the infant. While breastfeeding, the drug should not be applied to the breast area.
Children and infants
Children are subject to relatively delicate skin, the drug is more absorbed and can cause the desired effects more quickly. Therefore, careful monitoring is required when using 7-color medicine for young children. Not recommended for use with children under 1 year of age.
The patient is using drugs that interact with the 7-color Silkron drug
Everyone needs to keep their doctor informed about the products they are taking so they can develop a regimen that's right for you.
Silkron 7-color medicine has many uses, but if not used correctly, it will also lead to many unwanted effects. Therefore, those who intend to take medicine should consult a specialist to ensure their own safety.